Grixis is a world of death, darkness, undead, hatred, envy, and a lot of other bad things. Due to the predominance of undeath, it is possible to find undead versions of Bant's leotaus and Jund's viashinos in Grixis. Before Grixis split off from the mega-plane of Alara, things were different. White and green mana still flourished there. The land was called Vithia, a white-aligned empire of humans and other races, a land proud of its dynasty of wise and honorable monarchs. 
Grixis features a vast wasteland known as the Dregscape which is dominated by demons, horrors, necromancers and other forms of undead.  The few living humans take shelter in hidden cities known as hermitages while the mutated ogres, known as incurables, dwell high in the mountains. The kathari occupy the islands out to sea.
The mages of Grixis hunt for the ultimate powers to conquer all others. They also harvest a strange gas-like material called "Vis," which is how they hang on to Grixis's small traces of life. The undead of Grixis live in the hellish landscape. They live (un-live?) there and rot to death, then rise again. There is no order, yet things are not as wild as in Jund, for without green and with blue, things are more controlled and not completely designed around instinct.
- The Boneheaps, the dumping grounds of the Kathari.
- The Droning Isles, the massive hives of the banewasps.
- Kederekt, a necropolis of undead-afflicted, half-sunken manor houses near a greasy sea.
- Sedraxis, once the shining capital of Vithia, now the greatest necropolis on the plane.
- Torchlight, the greatest hermitage of living beings.
- Unx, a necropolis most well known for the massive dragon skeleton that circles the city. It was once a grand stadium.
When the Conflux hit the shards, the life energies of green and white mana flooded into Grixis. The process of harvesting vis was disrupted, and the creatures became fueled with energy by the power of the life that was coming in. They invaded the nearby planes, turning dead soldiers into new undead of their own. Meanwhile, the great Dragon, Nicol Bolas, had already disrupted the other shards, and the plane fell into chaos. It has become part of the New Alara, and cults of demon worship have risen all across the new landscape, with the most notable being dedicated to Nefarox.
- Eliza of the Keep
- Nefarox, overlord of Grixis
- Sedris, the Vithian traitor king
- Grixis is the ancient Vithian word for traitor.
- Magic Arcana. (August 14, 2008.) "Shard Preview: Grixis", Daily MTG, magicthegathering.com, Wizards of the Coast.
- Mark Rosewater. (October 20, 2008.) "Looking Out For Number One", Daily MTG, magicthegathering.com, Wizards of the Coast.
- Doug Beyer. (September 24, 2008.) "Alive and Unwell", Daily MTG, magicthegathering.com, Wizards of the Coast.
- Mike Turian. (September 12, 2008.) "The Specter of the Present", Daily MTG, magicthegathering.com, Wizards of the Coast.
|Expansions: Shards of Alara | Conflux | Alara Reborn|
|Shards: Bant | Esper | Grixis | Jund | Naya|
|Characters: Ajani | Elspeth Tirel | Nicol Bolas | Rafiq | Sarkhan Vol | Tezzeret|
|Others: Etherium | Jazal | Kathari | Leotau | Maelstrom|